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This website serves as the online dispensary of Board Certified Nutritionist, Dr. Joseph Debé. It is the culmination of thousands of hours of study and scrutiny of nutritional supplements over the past 25 years. I offer the best professional quality supplements.



Supplements II

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60 capsules

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PrimAGE is a supplement containing two forms of vitamin B-6: pyridoxamine and pyridoxal-5'-phosphate (P5P). The role of P5P is to slow the body’s conversion of pyridoxamine to other substances, thereby prolonging its activity. (Ordinary vitamin B-6 supplements contain neither of these substances.)

While pyridoxamine, like all B vitamins, is involved in the conversion of food into energy, its most exciting property was only discovered in the 1990s: pyridoxamine inhibits the formation of ‘Advanced Glycation End-products’ (AGEs).

AGEs are damaged proteins that accumulate in the body as one ages, causing tissues to lose their elasticity and causing enzymes to malfunction. In fact, this accumulation of AGEs is considered to be one of the principal causes of aging.

AGEs also play a major role in diabetes — they may account for much of the tissue damage that is seen in the diabetic state — including damage to kidneys (nephropathy), nerves (neuropathy), vasculature (atherosclerosis), and eyes (retinopathy, cataracts).

Yet another remarkable property of pyridoxamine was announced by researchers in 2009: pyridoxamine neutralizes the destructive substances produced in the body by radioactive exposure — such as the exposure that occurs after a nuclear power plant accident.

PrimAGE therefore has four important applications:

  • slowing the aging process
  • inhibiting diabetes-related damage to the body
  • preventing radiation poisoning
  • helping to extract energy from food.